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Discovery of triarylethanolamine inhibitors of the Kv1.5 potassium channel

Academic Article
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Overview

authors

  • Beshore, D. C.
  • Liverton, N. J.
  • McIntyre, C. J.
  • Claiborne, Christopher Fairman
  • Libby, B.
  • Culberson, J. C.
  • Salata, J. J.
  • Regan, C. P.
  • Lynch, J. J.
  • Kiss, L.
  • Spencer, R. H.
  • Kane, S. A.
  • White, R. B.
  • Yeh, S.
  • Hartman, G. D.
  • Dinsmore, C. J.

publication date

  • April 2010

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Animals
  • Dose-Response Relationship, Drug
  • Drug Discovery
  • Drug Evaluation, Preclinical
  • Ethanolamines
  • Humans
  • Potassium Channel Blockers
  • Potassium Channels, Voltage-Gated
  • Structure-Activity Relationship
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Research

keywords

  • Arrhythmia
  • Atrial fibrillation
  • Kv1.5
  • TAEA
  • Triarylethanolamine
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2010.03.005

PubMed ID

  • 20304642
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Additional Document Info

start page

  • 2493

end page

  • 2496

volume

  • 20

issue

  • 8

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