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Discovery of a 3-amino-6-phenyl-pyridazine derivative as a new synthetic antineuroinflammatory compound

Academic Article
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  • Overview
  • Identity
  • Additional Document Info
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Overview

authors

  • Mirzoeva, S.
  • Sawkar, Anupama
  • Zasadzki, M.
  • Guo, L.
  • Velentza, A. V.
  • Dunlap, V.
  • Bourguignon, J. J.
  • Ramstrom, H.
  • Haiech, J.
  • Van Eldik, L. J.
  • Watterson, D. M.

publication date

  • 2002

journal

  • Journal of Medicinal Chemistry  Journal

subject areas

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal
  • Astrocytes
  • Calcium-Calmodulin-Dependent Protein Kinase Type 2
  • Calcium-Calmodulin-Dependent Protein Kinases
  • Cells, Cultured
  • Central Nervous System Agents
  • Drug Evaluation, Preclinical
  • Enzyme Inhibitors
  • Interleukin-1
  • Microglia
  • Nitric Oxide
  • Nitric Oxide Synthase
  • Nitric Oxide Synthase Type II
  • Pyridazines
  • Rats
  • Structure-Activity Relationship
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Identity

International Standard Serial Number (ISSN)

  • 0022-2623

Digital Object Identifier (DOI)

  • 10.1021/jm015573g

PubMed ID

  • 11806708
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Additional Document Info

start page

  • 563

end page

  • 566

volume

  • 45

issue

  • 3

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