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Neutralization takes precedence over IgG or IgA isotype-related functions in mucosal HIV-1 antibody-mediated protection

Academic Article
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Overview

authors

  • Astronomo, Rena
  • Santra, S.
  • Ballweber-Fleming, L.
  • Westerberg, K. G.
  • Mach, L.
  • Hensley-McBain, T.
  • Sutherland, L.
  • Mildenberg, B.
  • Morton, G.
  • Yates, N. L.
  • Mize, G. J.
  • Pollara, J.
  • Hladik, F.
  • Ochsenbauer, C.
  • Denny, T. N.
  • Warrier, R.
  • Rerks-Ngarm, S.
  • Pitisuttithum, P.
  • Nitayapan, S.
  • Kaewkungwal, J.
  • Ferrari, G.
  • Shaw, G. M.
  • Xia, S. M.
  • Liao, H. X.
  • Montefiori, D. C.
  • Tomaras, G. D.
  • Haynes, B. F.
  • McElrath, M. J.

publication date

  • December 2016

journal

  • EBiomedicine  Journal

subject areas

  • Animals
  • Antibodies, Neutralizing
  • Biomarkers
  • Disease Models, Animal
  • Female
  • HIV Antibodies
  • HIV Infections
  • HIV-1
  • Humans
  • Immunity, Mucosal
  • Immunoglobulin A
  • Immunoglobulin G
  • Immunophenotyping
  • Leukocytes
  • Macaca mulatta
  • Mucous Membrane
  • Neutralization Tests
  • Simian Acquired Immunodeficiency Syndrome
  • Simian Immunodeficiency Virus
  • Vagina
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Research

keywords

  • Antibodies
  • HIV-1
  • IgA
  • IgG
  • Mucosal immunology
  • Neutralizing antibodies
  • Non-human primate rectal challenge model
  • Vaginal explants
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Identity

PubMed Central ID

  • PMC5161443

International Standard Serial Number (ISSN)

  • 2352-3964

Digital Object Identifier (DOI)

  • 10.1016/j.ebiom.2016.11.024

PubMed ID

  • 27919754
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Additional Document Info

start page

  • 97

end page

  • 111

volume

  • 14

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