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The polymorphic human glutathione transferase T1-1, the most efficient glutathione transferase in the denitrosation and inactivation of the anticancer drug 1,3-bis(2-chloroethyl)-1-nitro sourea

Academic Article
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Overview

authors

  • Lien, S.
  • Larsson, A. K.
  • Mannervik, Bengt

publication date

  • January 2002

journal

  • Biochemical Pharmacology  Journal

subject areas

  • Amino Acids
  • Antineoplastic Agents
  • Binding, Competitive
  • Carmustine
  • Drug Resistance
  • Glutathione Transferase
  • Humans
  • Kinetics
  • Polymorphism, Genetic
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Research

keywords

  • BCNU
  • denitrosation
  • drug resistance
  • glutathione transferase
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Identity

International Standard Serial Number (ISSN)

  • 0006-2952

Digital Object Identifier (DOI)

  • 10.1016/s0006-2952(01)00846-2

PubMed ID

  • 11841793
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Additional Document Info

start page

  • 191

end page

  • 197

volume

  • 63

issue

  • 2

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