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Tripolar chromosome segregation drives the association between maternal genotype at variants spanning PLK4 and aneuploidy in human preimplantation embryos

Academic Article
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Overview

authors

  • McCoy, R. C.
  • Newnham, L. J.
  • Ottolini, C. S.
  • Hoffmann, E. R.
  • Chatzimeletiou, K.
  • Cornejo, O. E.
  • Zhan, Q.
  • Zaninovic, N.
  • Rosenwaks, Z.
  • Petrov, D. A.
  • Demko, Zachary
  • Sigurjonsson, S.
  • Handyside, A. H.

publication date

  • July 2018

journal

  • Human Molecular Genetics  Journal

subject areas

  • Adolescent
  • Adult
  • Aneuploidy
  • Blastocyst
  • Blastomeres
  • Chromosome Segregation
  • Female
  • Genetic Testing
  • Genetic Variation
  • Genotype
  • Humans
  • Karyotype
  • Maternal Age
  • Middle Aged
  • Mitosis
  • Oogenesis
  • Pregnancy
  • Protein-Serine-Threonine Kinases
  • Spindle Apparatus
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Identity

PubMed Central ID

  • PMC6030883

International Standard Serial Number (ISSN)

  • 0964-6906

Digital Object Identifier (DOI)

  • 10.1093/hmg/ddy147

PubMed ID

  • 29688390
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Additional Document Info

start page

  • 2573

end page

  • 2585

volume

  • 27

issue

  • 14

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