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Identification of potent Yes1 kinase inhibitors using a library screening approach

Academic Article
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Overview

authors

  • Patel, Paresma
  • Sun, H.
  • Li, S. Q.
  • Shen, M.
  • Khan, J.
  • Thomas, C. J.
  • Davis, M. I.

publication date

  • August 2013

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Binding Sites
  • Cell Line
  • Cell Survival
  • Drug Design
  • Humans
  • Hydrogen Bonding
  • Molecular Docking Simulation
  • Protein Kinase Inhibitors
  • Protein Structure, Tertiary
  • Proto-Oncogene Proteins c-yes
  • Small Molecule Libraries
  • Structure-Activity Relationship
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Research

keywords

  • HTS
  • Inhibitor
  • Kinase
  • Rhabdomyosarcoma
  • Screening
  • Small molecule
  • Yes1
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Identity

PubMed Central ID

  • PMC3769177

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2013.05.072

PubMed ID

  • 23787099
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Additional Document Info

start page

  • 4398

end page

  • 4403

volume

  • 23

issue

  • 15

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