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N-terminus alkylation of vancomycin: ligand binding affinity, antimicrobial activity, and site-specific nature of quaternary trimethylammonium salt modification

Academic Article
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Overview

related to degree

  • Wu, Zhichen, Ph.D. in Chemistry, Scripps Research 2017 -

authors

  • Wu, Zhichen
  • Isley, N. A.
  • Boger, Dale

publication date

  • October 2018

journal

  • ACS Infectious Diseases  Journal
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Research

keywords

  • glycopeptide antibiotics
  • membrane permeabilization
  • site-specific mechanism of action
  • vancomycin
  • vancomycin peripheral modification
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Identity

PubMed Central ID

  • PMC6200594

International Standard Serial Number (ISSN)

  • 2373-8227

Digital Object Identifier (DOI)

  • 10.1021/acsinfecdis.8b00152

PubMed ID

  • 30067012
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Additional Document Info

start page

  • 1468

end page

  • 1474

volume

  • 4

issue

  • 10

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