related to degree

• Glinkerman, Christopher, Ph.D. in Chemistry, Scripps Research 2013 - 2018
• Anderson, Erin, Ph.D. in Organic Chemistry, Scripps Research 2007 - 2013

authors

• Anderson, Erin
• Duerfeldt, A. S.
• Zhu, K.
• Glinkerman, Christopher
• Boger, Dale

publication date

• October 2014

journal

• Organic Letters  Journal

abstract

• The scope of the [4 + 2] cycloaddition reactions of substituted 1,2,3-triazines, bearing noncomplementary substitution with electron-withdrawing groups at C4 and/or C6, is described. The studies define key electronic and steric effects of substituents impacting the reactivity, mode (C4/N1 vs C5/N2), and regioselectivity of the cycloaddition reactions of 1,2,3-triazines with amidines, enamines, and ynamines, providing access to highly functionalized heterocycles.

subject areas

• Cycloaddition Reaction
• Molecular Structure
• Stereoisomerism
• Triazines

PubMed Central ID

• PMC4184932

International Standard Serial Number (ISSN)

• 1523-7060

Digital Object Identifier (DOI)

• 10.1021/ol502436n

PubMed ID

• 25222918

start page

• 5084

end page

• 5087

volume

• 16

issue

• 19