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Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

Academic Article
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  • Identity
  • Additional Document Info
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Overview

authors

  • Lama, L.
  • Adura, C.
  • Xie, W.
  • Tomita, D.
  • Kamei, T.
  • Kuryavyi, V.
  • Gogakos, T.
  • Steinberg, J. I.
  • Miller, M.
  • Ramos-Espiritu, L.
  • Asano, Y.
  • Hashizume, S.
  • Aida, J.
  • Imaeda, T.
  • Okamoto, R.
  • Jennings, A. J.
  • Michino, Mayako
  • Kuroita, T.
  • Stamford, A.
  • Gao, P.
  • Meinke, P.
  • Glickman, J. F.
  • Patel, D. J.
  • Tuschl, T.

publication date

  • May 2019

journal

  • Nature Communications  Journal

subject areas

  • Autoimmune Diseases
  • Cells, Cultured
  • Crystallography, X-Ray
  • DNA
  • Drug Discovery
  • Enzyme Inhibitors
  • High-Throughput Screening Assays
  • Humans
  • Immunity, Innate
  • Interferons
  • Macrophages
  • Models, Molecular
  • Nucleotides, Cyclic
  • Nucleotidyltransferases
  • Primary Cell Culture
  • Recombinant Proteins
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Identity

PubMed Central ID

  • PMC6529454

International Standard Serial Number (ISSN)

  • 2041-1723

Digital Object Identifier (DOI)

  • 10.1038/s41467-019-08620-4

PubMed ID

  • 31113940
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Additional Document Info

volume

  • 10

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