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Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach

Academic Article
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  • Additional Document Info
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Overview

authors

  • Nonami, A.
  • Sattler, M.
  • Weisberg, E.
  • Liu, Q.
  • Zhang, J.
  • Patricelli, Matt
  • Christie, A. L.
  • Saur, A. M.
  • Kohl, N. E.
  • Kung, A. L.
  • Yoon, H.
  • Sim, T.
  • Gray, N. S.
  • Griffin, J. D.

publication date

  • May 2015

journal

  • Blood  Journal

subject areas

  • Animals
  • Antineoplastic Agents
  • Apoptosis
  • Bicyclo Compounds, Heterocyclic
  • Cell Cycle Checkpoints
  • Cell Line, Tumor
  • Disease Models, Animal
  • Drug Screening Assays, Antitumor
  • GTP Phosphohydrolases
  • Humans
  • Leukemia
  • Membrane Proteins
  • Mice
  • Mutation
  • Protein Kinase Inhibitors
  • Protein-Serine-Threonine Kinases
  • Proto-Oncogene Proteins c-akt
  • Pyrimidinones
  • Signal Transduction
  • Small Molecule Libraries
  • Xenograft Model Antitumor Assays
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Identity

PubMed Central ID

  • PMC4432008

International Standard Serial Number (ISSN)

  • 0006-4971

Digital Object Identifier (DOI)

  • 10.1182/blood-2014-12-615906

PubMed ID

  • 25833960
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Additional Document Info

start page

  • 3133

end page

  • 3143

volume

  • 125

issue

  • 20

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