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Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity

Academic Article
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  • Research
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Overview

authors

  • Fass, D. M.
  • Reis, S. A.
  • Ghosh, B.
  • Hennig, K. M.
  • Joseph, Nadine
  • Zhao, W. N.
  • Nieland, T. J. F.
  • Guan, J. S.
  • Kuhnle, C. E. G.
  • Tang, W. P.
  • Barker, D. D.
  • Mazitschek, R.
  • Schreiber, S. L.
  • Tsai, L. H.
  • Haggarty, S. J.

publication date

  • January 2013

journal

  • Neuropharmacology  Journal

subject areas

  • Acetylation
  • Animals
  • Animals, Newborn
  • Biphenyl Compounds
  • Cells, Cultured
  • Dendrites
  • Drug Discovery
  • Embryo, Mammalian
  • Genes, Reporter
  • Histone Deacetylase Inhibitors
  • Histone Deacetylases
  • Histones
  • Hydrazines
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Transgenic
  • Nerve Tissue Proteins
  • Neuronal Plasticity
  • Neurons
  • Nootropic Agents
  • Prosencephalon
  • Recombinant Proteins
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Research

keywords

  • Acetylation
  • CREB
  • Chromatin
  • Cognitive enhancer
  • Epigenetic
  • Histone deacetylases
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Identity

PubMed Central ID

  • PMC3447535

International Standard Serial Number (ISSN)

  • 0028-3908

Digital Object Identifier (DOI)

  • 10.1016/j.neuropharm.2012.06.043

PubMed ID

  • 22771460
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Additional Document Info

start page

  • 81

end page

  • 96

volume

  • 64

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