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Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity

Academic Article
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Overview

authors

  • Johnson, Steven
  • Murphy, R. C.
  • Geiger, J. A.
  • DeRocher, A. E.
  • Zhang, Z.
  • Ojo, K. K.
  • Larson, E. T.
  • Perera, B. G. K.
  • Dale, E. J.
  • He, P.
  • Reid, M. C.
  • Fox, A. M. W.
  • Mueller, N. R.
  • Merritt, E. A.
  • Fan, E. K.
  • Parsons, M.
  • Van Voorhis, W. C.
  • Maly, D. J.

publication date

  • March 2012

journal

  • Journal of Medicinal Chemistry  Journal

subject areas

  • Cell Line
  • Cell Proliferation
  • Coccidiostats
  • Crystallography, X-Ray
  • Drug Resistance
  • Enzyme Assays
  • Humans
  • Models, Molecular
  • Molecular Structure
  • Naphthalenes
  • Piperidines
  • Protein Kinase Inhibitors
  • Protein Kinases
  • Protozoan Proteins
  • Pyrazoles
  • Pyrimidines
  • Structure-Activity Relationship
  • Toxoplasma
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Identity

PubMed Central ID

  • PMC3306180

International Standard Serial Number (ISSN)

  • 0022-2623

Digital Object Identifier (DOI)

  • 10.1021/jm201713h

PubMed ID

  • 22320388
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Additional Document Info

start page

  • 2416

end page

  • 2426

volume

  • 55

issue

  • 5

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