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An allosteric mechanism for drug block of the human cardiac potassium channel KCNQ1

Academic Article
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  • Identity
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Overview

authors

  • Yang, T.
  • Smith, Jarrod Anson
  • Leake, B. F.
  • Sanders, C. R.
  • Meiler, J.
  • Roden, D. M.

publication date

  • February 2013

journal

  • Molecular Pharmacology  Journal

subject areas

  • Alanine
  • Allosteric Regulation
  • Animals
  • Binding Sites
  • CHO Cells
  • Cell Line
  • Cricetinae
  • Cysteine
  • Heart
  • Humans
  • KCNQ1 Potassium Channel
  • Models, Molecular
  • Mutagenesis, Site-Directed
  • Myocardium
  • Quinidine
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Identity

PubMed Central ID

  • PMC3558809

International Standard Serial Number (ISSN)

  • 0026-895X

Digital Object Identifier (DOI)

  • 10.1124/mol.112.081513

PubMed ID

  • 23193163
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Additional Document Info

start page

  • 481

end page

  • 489

volume

  • 83

issue

  • 2

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