Expanding the functional role of long noncoding RNAs

Academic Article

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Overview

authors

• Johnsson, P.
• Morris, Kevin

publication date

• November 2014

journal

• Cell Research  Journal

abstract

• New findings bring to light a previously unappreciated mechanism involved in the regulation of the oncoprotein MYC. Interesting observations find that the long noncoding RNA (lncRNA) PVT1 is active in controlling levels of MYC through regulation of MYC protein stability.

subject areas

• Animals
• DNA Copy Number Variations
• Gene Amplification
• Gene Dosage
• Genes, myc
• Humans
• Oncogene Protein p55(v-myc)
• RNA, Long Noncoding

Identity

PubMed Central ID

• PMC4220152

International Standard Serial Number (ISSN)

• 1001-0602

Digital Object Identifier (DOI)

• 10.1038/cr.2014.104

PubMed ID

• 25104732

Additional Document Info

start page

• 1284

end page

• 1285

volume

• 24

issue

• 11