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The cancer drug dasatinib increases PGC-1α in adipose tissue but has adverse effects on glucose tolerance in obese mice

Academic Article
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Overview

authors

  • Sylow, L.
  • Long, Jonathan
  • Lokurkar, I. A.
  • Zeng, X.
  • Richter, E. A.
  • Spiegelman, B. M.

publication date

  • November 2016

journal

  • Endocrinology  Journal

subject areas

  • Adipocytes
  • Adipose Tissue
  • Animals
  • Blood Glucose
  • Cell Line
  • Cell Line, Tumor
  • Dasatinib
  • Glucose Tolerance Test
  • Glucose-6-Phosphatase
  • Immunoblotting
  • Insulin Resistance
  • Liver
  • Male
  • Mice
  • Mice, Obese
  • Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
  • Phosphoenolpyruvate Carboxykinase (ATP)
  • Polymerase Chain Reaction
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Identity

PubMed Central ID

  • PMC5086530

International Standard Serial Number (ISSN)

  • 0013-7227

Digital Object Identifier (DOI)

  • 10.1210/en.2016-1398

PubMed ID

  • 27589085
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Additional Document Info

start page

  • 4184

end page

  • 4191

volume

  • 157

issue

  • 11

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