recent publications
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academic article
- Lee, K., Elliott, H. L., Oak, Y., Zee, C. T., Groisman, A., Tytell, J. D., Danuser, G. Functional hierarchy of redundant actin assembly factors revealed by fine-grained registration of intrinsic image fluctuations Cell Systems 2015 1:37-50 DOI:10.1016/j.cels.2015.07.001 PMID:26273703 PMCID:PMC4530526
- Elliott, H., Fischer, R. S., Myers, K. A., Desai, R. A., Gao, L., Chen, C. S., Adelstein, R. S., Waterman, C. M., Danuser, G. Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature Nature Cell Biology 2015 17:137-147 DOI:10.1038/ncb3092 PMID:25621949 PMCID:PMC4312523
- Smole, Z., Thoma, C. R., Applegate, K. T., Duda, M., Gutbrodt, K. L., Danuser, G., Krek, W. Tumor suppressor NF2/Merlin is a microtubule stabilizer Cancer Research 2014 74:353-362 DOI:10.1158/0008-5472.can-13-1334 PMID:24282279 PMCID:PMC3929585
- Vilela, M., Halidi, N., Besson, S., Elliott, H., Hahn, K., Tytell, J., Danuser, G. Fluctuation analysis of activity biosensor images for the study of information flow in signaling pathways Methods in Enzymology 2013 519:253-276 DOI:10.1016/b978-0-12-405539-1.00009-9 PMID:23280114
- Marco, E., Dorn, J. F., Hsu, P. H., Jaqaman, K., Sorger, P. K., Danuser, G. S. cerevisiae chromosomes biorient via gradual resolution of syntely between S phase and anaphase Cell 2013 154:1127-1139 DOI:10.1016/j.cell.2013.08.008 PMID:23993100 PMCID:PMC3802543
- Nishimura, Y., Applegate, K., Davidson, M. W., Danuser, G., Waterman, C. M. Automated screening of microtubule growth dynamics identifies MARK2 as a regulator of leading edge microtubules downstream of Rac1 in migrating cells PLoS One 2012 7 DOI:10.1371/journal.pone.0041413 PMID:22848487 PMCID:PMC3404095
- Myers, K. A., Applegate, K. T., Danuser, G., Fischer, R. S., Waterman, C. M. Distinct ECM mechanosensing pathways regulate microtubule dynamics to control endothelial cell branching morphogenesis Journal of Cell Biology 2011 192:321-334 DOI:10.1083/jcb.201006009 PMID:21263030 PMCID:PMC3172168
- Mendoza, M. C., Er, E. E., Zhang, W., Ballif, B. A., Elliott, H. L., Danuser, G., Blenis, J. ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex Molecular Cell 2011 41:661-671 DOI:10.1016/j.molcel.2011.02.031 PMID:21419341 PMCID:PMC3078620
- Welch, C. M., Elliott, H., Danuser, G., Hahn, K. M. Imaging the coordination of multiple signalling activities in living cells Nature Reviews Molecular Cell Biology 2011 12:749-756 DOI:10.1038/nrm3212 PMID:22016058 PMCID:PMC3773929
- Applegate, K. T., Besson, S., Matov, A., Bagonis, M. H., Jaqaman, K., Danuser, G. plusTipTracker: Quantitative image analysis software for the measurement of microtubule dynamics Journal of Structural Biology 2011 176:168-184 DOI:10.1016/j.jsb.2011.07.009 PMID:21821130 PMCID:PMC3298692
- Matov, A., Applegate, K., Kumar, P., Thoma, C., Krek, W., Danuser, G., Wittmann, T. Analysis of microtubule dynamic instability using a plus-end growth marker Nature Methods 2010 7:761-768 DOI:10.1038/nmeth.1493 PMID:20729842 PMCID:PMC3032800
- Jaqaman, K., King, E. M., Amaro, A. C., Winter, J. R., Dorn, J. F., Elliott, H. L., McHedlishvili, N., McClelland, S. E., Porter, I. M., Posch, M., Toso, A., Danuser, G., et al. Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases Journal of Cell Biology 2010 188:665-679 DOI:10.1083/jcb.200909005 PMID:20212316 PMCID:PMC2835940
- Wilson, C. A., Tsuchida, M. A., Allen, G. M., Barnhart, E. L., Applegate, K. T., Yam, P. T., Ji, L., Keren, K., Danuser, G., Theriot, J. A. Myosin II contributes to cell-scale actin network treadmilling through network disassembly Nature 2010 465:373-377 DOI:10.1038/nature08994 PMID:20485438 PMCID:PMC3662466
- Lim, J. I., Sabouri-Ghomi, M., Machacek, M., Waterman, C. M., Danuser, G. Protrusion and actin assembly are coupled to the organization of lamellar contractile structures Experimental Cell Research 2010 316:2027-2041 DOI:10.1016/j.yexcr.2010.04.011 PMID:20406634 PMCID:PMC2900543
- Machacek, M., Hodgson, L., Welch, C., Elliott, H., Pertz, O., Nalbant, P., Abell, A., Johnson, G. L., Hahn, K. M., Danuser, G. Coordination of Rho GTPase activities during cell protrusion Nature 2009 461:99-103 DOI:10.1038/nature08242 PMID:19693013 PMCID:PMC2885353
- Lim, J., Danuser, G. Live cell imaging of F-actin dynamics via Fluorescent Speckle Microscopy (FSM) Journal of Visualized Experiments : JoVE 2009 DOI:10.3791/1325 PMID:19684563 PMCID:PMC3149907
- Dorn, J. F., Danuser, G., Yang, G. Computational processing and analysis of dynamic fluorescence image data Methods in Cell Biology 2008 85:497-538 DOI:10.1016/s0091-679x(08)85022-4
- Ji, L., Lim, J., Danuser, G. Fluctuations of intracellular forces during cell protrusion Nature Cell Biology 2008 10:1393-1400 DOI:10.1038/ncb1797 PMID:19011623 PMCID:PMC2597050
- Hu, Ke and Ji, Lin, Applegate, Kathryn T., Danuser, Gaudenz, Waterman-Storer, Clare M. Differential transmission of actin motion within focal adhesions Science 2007 315:111-115 DOI:10.1126/science.1135085 PMID:17204653
- Jaqaman, K., Dorn, J. F., Marco, E., Sorger, P. K., Danuser, G. Phenotypic clustering of yeast mutants based on kinetochore microtubule dynamics Bioinformatics 2007 23:1666-1673 DOI:10.1093/bioinformatics/btm230
- Soutoglou, E., Dorn, J. F., Sengupta, K., Jasin, M., Nussenzweig, A., Ried, T., Danuser, G., Misteli, T. Positional stability of single double-strand breaks in mammalian cells Nature Cell Biology 2007 9:675-682 DOI:10.1038/ncb1591 PMID:17486118 PMCID:PMC2442898
- Jaqaman, K., Dorn, J. F., Jelson, G. S., Tytell, J. D., Sorger, P. K., Danuser, G. Comparative autoregressive moving average analysis of kinetochore microtubule dynamics in yeast Biophysical Journal 2006 91:2312-2325 DOI:10.1529/biophysj.106.080333
- Dorn, J. F., Jaqaman, K., Rines, D. R., Jelson, G. S., Sorger, P. K., Danuser, G. Yeast kinetochore microtubule dynamics analyzed by high-resolution three-dimensional microscopy Biophysical Journal 2005 89:2835-2854 DOI:10.1529/biophysj.104.058461
- Thomann, D., Dorn, J., Sorger, P. K., Danuser, G. Automatic fluorescent tag localization II: improvement in super-resolution by relative tracking Journal of Microscopy-Oxford 2003 211:230-248 DOI:10.1046/j.1365-2818.2003.01223.x