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Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors

Academic Article
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  • Research
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Overview

authors

  • Zhu, Y.
  • Tchkonia, T.
  • Fuhrmann-Stroissnigg, H.
  • Dai, H. M. M.
  • Ling, Y. Y. Y.
  • Stout, M. B.
  • Pirtskhalava, T.
  • Giorgadze, N.
  • Johnson, K. O.
  • Giles, C. B.
  • Wren, J. D.
  • Niedernhofer, Laura
  • Robbins, Paul D.
  • Kirkland, J. L.

publication date

  • June 2016

journal

  • Aging Cell  Journal
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Research

keywords

  • ABT-263
  • Bcl-2 family
  • TW-37
  • dasatinib
  • quercetin
  • senescent cells
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Identity

PubMed Central ID

  • PMC4854923

International Standard Serial Number (ISSN)

  • 1474-9718

Digital Object Identifier (DOI)

  • 10.1111/acel.12445

PubMed ID

  • 26711051
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Additional Document Info

start page

  • 428

end page

  • 435

volume

  • 15

issue

  • 3

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