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Affinity maturation of a potent family of HIV antibodies is primarily focused on accommodating or avoiding glycans

Academic Article
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Overview

related to degree

  • Puchades Garcia, Cristina, Ph.D. in Biophysics, Scripps Research 2014 -
  • Lee, Jeong Hyun, Ph.D. in Chemical Biology, Scripps Research 2011 - 2016

authors

  • Garces, F.
  • Lee, Jeong Hyun
  • de Val, N.
  • Torrents de la Peña, A.
  • Kong, L.
  • Puchades Garcia, Cristina
  • Hua, Y.
  • Stanfield, Robyn
  • Burton, Dennis
  • Moore, J. P.
  • Sanders, R. W.
  • Ward, Andrew
  • Wilson, Ian

publication date

  • December 2015

journal

  • Immunity  Journal

subject areas

  • Antibodies, Neutralizing
  • Antibody Affinity
  • Antigens, Viral
  • Calorimetry, Differential Scanning
  • Crystallography, X-Ray
  • Epitopes
  • HEK293 Cells
  • HIV Antibodies
  • HIV-1
  • Humans
  • Image Processing, Computer-Assisted
  • Microscopy, Electron, Transmission
  • Mutagenesis, Site-Directed
  • Polysaccharides
  • Somatic Hypermutation, Immunoglobulin
  • Viral Envelope Proteins
  • X-Ray Diffraction
  • env Gene Products, Human Immunodeficiency Virus
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Identity

PubMed Central ID

  • PMC4692269

International Standard Serial Number (ISSN)

  • 1074-7613

Digital Object Identifier (DOI)

  • 10.1016/j.immuni.2015.11.007

PubMed ID

  • 26682982
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Additional Document Info

start page

  • 1053

end page

  • 1063

volume

  • 43

issue

  • 6

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