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Treatment of mice with human monoclonal antibody 24 h after lethal aerosol challenge with virulent Venezuelan equine encephalitis virus prevents disease but not infection

Academic Article
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Overview

authors

  • Hunt, A. R.
  • Bowen, R. A.
  • Barbas-Frederickson, Shana
  • Maruyama, T.
  • Roehrig, J. T.
  • Blair, C. D.

publication date

  • June 2011

journal

  • Virology  Journal

subject areas

  • Animals
  • Antibodies, Monoclonal
  • Antibodies, Viral
  • Cell Line
  • Disease Models, Animal
  • Encephalitis Virus, Venezuelan Equine
  • Encephalomyelitis, Venezuelan Equine
  • Female
  • Humans
  • Male
  • Mice
  • Mice, Inbred ICR
  • Neutralization Tests
  • Post-Exposure Prophylaxis
  • Viral Envelope Proteins
  • Virulence
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Research

keywords

  • Alphavirus
  • Antibody prophylaxis
  • Antibody therapy
  • Envelope glycoprotein
  • Human monoclonal antibody
  • Venezuelan equine encephalitis virus
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Identity

PubMed Central ID

  • PMC3097527

International Standard Serial Number (ISSN)

  • 0042-6822

Digital Object Identifier (DOI)

  • 10.1016/j.virol.2011.03.016

PubMed ID

  • 21489591
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Additional Document Info

start page

  • 146

end page

  • 152

volume

  • 414

issue

  • 2

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