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Syntheses of novel myxopyronin B analogs as potential inhibitors of bacterial RNA polymerase

Academic Article
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  • Research
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Overview

authors

  • Lira, Ricardo
  • Xiang, A. X.
  • Doundoulakis, T.
  • Biller, W. T.
  • Agrios, K. A.
  • Simonsen, K. B.
  • Webber, S. E.
  • Sisson, W.
  • Aust, R. M.
  • Shah, A. M.
  • Showalter, R. E.
  • Banh, V. N.
  • Steffy, K. R.
  • Appleman, J. R.

publication date

  • December 2007

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Anti-Bacterial Agents
  • DNA-Directed RNA Polymerases
  • Enzyme Inhibitors
  • Escherichia coli
  • Inhibitory Concentration 50
  • Lactones
  • Methylation
  • Molecular Structure
  • Staphylococcus aureus
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Research

keywords

  • antibacterial
  • antibiotics
  • curtius rearrangement
  • myxopyronin B
  • ortholithiation
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2007.10.017

PubMed ID

  • 17980587
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Additional Document Info

start page

  • 6797

end page

  • 6800

volume

  • 17

issue

  • 24

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