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Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors

Academic Article
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Overview

authors

  • Jiang, J. K.
  • Huang, X.
  • Shamim, K.
  • Patel, Paresma
  • Lee, A.
  • Wang, A. Q.
  • Nguyen, K.
  • Tawa, G.
  • Cuny, G. D.
  • Yu, P. B.
  • Zheng, W.
  • Xu, X.
  • Sanderson, P.
  • Huang, W.

publication date

  • November 2018

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Activin Receptors, Type I
  • Animals
  • Binding Sites
  • Drug Discovery
  • Humans
  • Mice, Inbred C57BL
  • Molecular Structure
  • Protein Kinase Inhibitors
  • Pyrazoles
  • Pyrimidines
  • Structure-Activity Relationship
  • Sulfonamides
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Identity

PubMed Central ID

  • PMC6218249

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2018.09.006

PubMed ID

  • 30227946
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Additional Document Info

start page

  • 3356

end page

  • 3362

volume

  • 28

issue

  • 20

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