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Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: A novel excitoprotective mechanism involving modulation of tau phosphorylation

Academic Article
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  • Overview
  • Research
  • Identity
  • Additional Document Info
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Overview

authors

  • Han, P.
  • Dou, F.
  • Li, F.
  • Zhang, X.
  • Zhang, Y. W.
  • Zheng, H.
  • Lipton, Stuart
  • Xu, H.
  • Liao, F. F.

publication date

  • December 2005

journal

  • Journal of Neuroscience  Journal

subject areas

  • Amyloid beta-Protein Precursor
  • Animals
  • Cell Line, Tumor
  • Cyclin-Dependent Kinase 5
  • Enzyme Activation
  • Enzyme Inhibitors
  • Humans
  • Mice
  • Mice, Knockout
  • Neuroprotective Agents
  • Phosphorylation
  • Protein Structure, Tertiary
  • Rats
  • Rats, Sprague-Dawley
  • tau Proteins
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Research

keywords

  • CDK5
  • beta-amyloid precursor protein
  • excitotoxicity
  • neurite outgrowth
  • phosphorylation
  • tau
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Identity

International Standard Serial Number (ISSN)

  • 0270-6474

Digital Object Identifier (DOI)

  • 10.1523/jneurosci.3831-05.2005

PubMed ID

  • 16354912
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Additional Document Info

start page

  • 11542

end page

  • 11552

volume

  • 25

issue

  • 50

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