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Identification of a novel drug lead that inhibits HCV infection and cell-to-cell transmission by targeting the HCV E2 glycoprotein

Academic Article
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Overview

authors

  • Al Olaby, R. R.
  • Cocquerel, L.
  • Zemla, A.
  • Saas, L.
  • Dubuisson, J.
  • Vielmetter, J.
  • Marcotrigiano, J.
  • Khan, A. G.
  • Catalan, F. V.
  • Perryman, A. L.
  • Freundlich, J. S.
  • Forli, Stefano
  • Levy, S.
  • Balhorn, R.
  • Azzazy, H. M.

publication date

  • October 2014

journal

  • PLoS One  Journal

subject areas

  • Amino Acid Sequence
  • Antigens, CD81
  • Antiviral Agents
  • Binding Sites
  • Cell Line, Tumor
  • Cell Survival
  • Crystallography, X-Ray
  • Genotype
  • Hepacivirus
  • Hepatitis C
  • Humans
  • Kinetics
  • Ligands
  • Models, Molecular
  • Molecular Sequence Data
  • Protein Binding
  • Recombinant Proteins
  • Structural Homology, Protein
  • Surface Plasmon Resonance
  • Thermodynamics
  • Viral Envelope Proteins
  • Virus Internalization
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Identity

PubMed Central ID

  • PMC4214736

International Standard Serial Number (ISSN)

  • 1932-6203

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0111333

PubMed ID

  • 25357246
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Additional Document Info

volume

  • 9

issue

  • 10

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