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Selective vasopressin-1a receptor antagonist prevents brain edema, reduces astrocytic cell swelling and GFAP, V1aR and AQP4 expression after focal traumatic brain injury

Academic Article
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Overview

authors

  • Marmarou, C. R.
  • Liang, X.
  • Abidi, N. H.
  • Parveen, S.
  • Taya, K.
  • Henderson, Scott
  • Young, H. F.
  • Filippidis, A. S.
  • Baumgarten, C. M.

publication date

  • September 2014

journal

  • Brain Research  Journal

subject areas

  • Animals
  • Antidiuretic Hormone Receptor Antagonists
  • Aquaporin 4
  • Astrocytes
  • Brain Edema
  • Brain Injuries
  • Disease Models, Animal
  • Gene Expression
  • Glial Fibrillary Acidic Protein
  • Immunohistochemistry
  • Indoles
  • Male
  • Microscopy, Confocal
  • Neuroprotective Agents
  • Pyrrolidines
  • Random Allocation
  • Rats
  • Rats, Sprague-Dawley
  • Receptors, Vasopressin
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Research

keywords

  • Aquaporin 4
  • Astrocyte
  • Edema
  • SR49059
  • Traumatic brain injury
  • Vasopressin
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Identity

PubMed Central ID

  • PMC4240002

International Standard Serial Number (ISSN)

  • 0006-8993

Digital Object Identifier (DOI)

  • 10.1016/j.brainres.2014.06.005

PubMed ID

  • 24933327
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Additional Document Info

start page

  • 89

end page

  • 102

volume

  • 1581

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