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Kinetic characterization of recombinant human glutathione transferase T1-1, a polymorphic detoxication enzyme

Academic Article
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Overview

authors

  • Jemth, P.
  • Mannervik, Bengt

publication date

  • December 1997

journal

  • Archives of Biochemistry and Biophysics  Journal

subject areas

  • Chromatography, Affinity
  • Cloning, Molecular
  • Epoxy Compounds
  • Escherichia coli
  • Glutathione
  • Glutathione Transferase
  • Humans
  • Hydrogen-Ion Concentration
  • Kinetics
  • Nitrobenzenes
  • Nitrophenols
  • Recombinant Proteins
  • Sequence Analysis, DNA
  • Substrate Specificity
  • Sulfhydryl Compounds
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Research

keywords

  • 1,2-epoxy-3-(4-nitrophenoxy)propane
  • EPNP
  • glutathione transferase
  • pH dependence
  • steady state kinetics
  • substrate selectivity
  • theta class glutathione transferase
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Identity

International Standard Serial Number (ISSN)

  • 0003-9861

Digital Object Identifier (DOI)

  • 10.1006/abbi.1997.0357

PubMed ID

  • 9434735
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Additional Document Info

start page

  • 247

end page

  • 254

volume

  • 348

issue

  • 2

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