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Metabolic reprogramming ensures cancer cell survival despite oncogenic signaling blockade

Academic Article
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Overview

authors

  • Lue, H. W.
  • Podolak, J.
  • Kolahi, K.
  • Cheng, L.
  • Rao, S.
  • Garg, D.
  • Xue, C. H.
  • Rantala, J. K.
  • Tyner, J. W.
  • Thornburg, K. L.
  • Martinez-Acevedo, A.
  • Liu, J. J.
  • Amling, C. L.
  • Truillet, C.
  • Louie, S. M.
  • Anderson, K. E.
  • Evans, Michael
  • O'Donnell, V. B.
  • Nomura, D. K.
  • Drake, J. M.
  • Ritz, A.
  • Thomas, G. V.

publication date

  • 2017

journal

  • Genes & Development  Journal

subject areas

  • Animals
  • Antineoplastic Agents
  • Apoptosis
  • Autophagy
  • Benzamides
  • Cell Line, Tumor
  • Cell Respiration
  • Cell Survival
  • Heterocyclic Compounds, 3-Ring
  • Humans
  • Lipid Droplets
  • Mice
  • Mitochondria
  • Neoplasms
  • Phosphatidylinositol 3-Kinases
  • Phospholipase A2 Inhibitors
  • Phospholipids
  • Protein Kinase Inhibitors
  • Proto-Oncogene Proteins c-akt
  • Pyrimidines
  • Signal Transduction
  • Tumor Cells, Cultured
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Research

keywords

  • autophagy
  • cancer
  • metabolism
  • phospholipid
  • resistance
  • signaling
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Identity

PubMed Central ID

  • PMC5733498

International Standard Serial Number (ISSN)

  • 0890-9369

Digital Object Identifier (DOI)

  • 10.1101/gad.305292.117

PubMed ID

  • 29138276
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Additional Document Info

start page

  • 2067

end page

  • 2084

volume

  • 31

issue

  • 20

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