Novel PTP1B inhibitors identified by DNA display of fragment pairs

Academic Article

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• Research
• Identity
• Additional Document Info
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Overview

authors

• Barluenga, S.
• Zambaldo, C.
• Ioannidou, H. A.
• Ciobanu, M.
• Morieux, P.
• Daguer, J. P.
• Winssinger, Nicolas

publication date

• 2016

journal

• Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

• DNA
• Enzyme Inhibitors
• Humans
• Microarray Analysis
• Peptide Nucleic Acids
• Protein Binding
• Protein Tyrosine Phosphatase, Non-Receptor Type 1
• Small Molecule Libraries

Research

keywords

• DNA-encoded library
• Fragment based drug discovery
• PTP1B
• Peptide nucleic acid (PNA)

Identity

International Standard Serial Number (ISSN)

• 0960-894X

Digital Object Identifier (DOI)

• 10.1016/j.bmcl.2015.11.102

PubMed ID

• 26691757

Additional Document Info

start page

• 1080

end page

• 1085

volume

• 26

issue

• 3