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Novel PTP1B inhibitors identified by DNA display of fragment pairs

Academic Article
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Overview

authors

  • Barluenga, S.
  • Zambaldo, C.
  • Ioannidou, H. A.
  • Ciobanu, M.
  • Morieux, P.
  • Daguer, J. P.
  • Winssinger, Nicolas

publication date

  • February 2016

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • DNA
  • Enzyme Inhibitors
  • Humans
  • Microarray Analysis
  • Peptide Nucleic Acids
  • Protein Binding
  • Protein Tyrosine Phosphatase, Non-Receptor Type 1
  • Small Molecule Libraries
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Research

keywords

  • DNA-encoded library
  • Fragment based drug discovery
  • PTP1B
  • Peptide nucleic acid (PNA)
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2015.11.102

PubMed ID

  • 26691757
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Additional Document Info

start page

  • 1080

end page

  • 1085

volume

  • 26

issue

  • 3

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