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Serine/threonine phosphatases of the pufferfish, Fugu rubripes

Academic Article
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Overview

authors

  • Koh, C. G.
  • Oon, S. H.
  • Brenner, Sydney

publication date

  • October 1997

journal

  • Gene  Journal

abstract

  • The compact genome of the Japanese pufferfish, Fugu rubripes, about 7.5 times smaller than the human genome, facilitates the isolation of vertebrate genes. We have used this genome to isolate and characterize members of the vertebrate serine/threonine protein phosphatase gene family. Our data reveal the presence of two isoforms of PP2A, alpha and beta, and PPX, as previously found in mammals.

subject areas

  • Amino Acid Sequence
  • Animals
  • Cloning, Molecular
  • Fishes, Poisonous
  • Genes
  • Humans
  • Introns
  • Molecular Sequence Data
  • Phosphoprotein Phosphatases
  • Polymerase Chain Reaction
  • RNA Splicing
  • RNA, Messenger
  • Sequence Alignment
  • Sequence Homology, Amino Acid
  • Species Specificity
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Research

keywords

  • PCR
  • comparative genome study
  • conservation of gene structures
  • small introns
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Identity

International Standard Serial Number (ISSN)

  • 0378-1119

Digital Object Identifier (DOI)

  • 10.1016/s0378-1119(97)00318-1

PubMed ID

  • 9370285
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Additional Document Info

start page

  • 223

end page

  • 228

volume

  • 198

issue

  • 1-2

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