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academic article
- Hughes, R. O., Rogier, D. J., Devraj, R., Zheng, C. S., Cao, G. F., Feng, H., Xia, M., Anand, R., Xing, L., Glenn, J., Zhang, K., Covington, M., et al. Discovery of ((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-4-ylamino) cyclopentyl)(4-(5-(trifluoromethyl)pyridazin-3-yl)piperazin-1-yl)methano ne, PF-4254196, a CCR2 antagonist with an improved cardiovascular profile Bioorganic & Medicinal Chemistry Letters 2011 21:2626-2630 DOI:10.1016/j.bmcl.2011.01.034 PMID:21315584