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In vivo efficacy of natural product-inspired irreversible kinase inhibitors

Academic Article
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Overview

authors

  • Barluenga, S.
  • Jogireddy, R.
  • Koripelly, G. K.
  • Winssinger, Nicolas

publication date

  • August 2010

journal

  • ChemBioChem  Journal

subject areas

  • Angiogenesis Inhibitors
  • Animals
  • Carcinoma, Renal Cell
  • Cell Growth Processes
  • Cell Line, Tumor
  • Female
  • Inhibitory Concentration 50
  • Kidney Neoplasms
  • Lactones
  • Mice
  • Mice, Inbred BALB C
  • Protein Kinase Inhibitors
  • Random Allocation
  • Receptor, Platelet-Derived Growth Factor beta
  • Vascular Endothelial Growth Factor Receptor-1
  • Xenograft Model Antitumor Assays
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Research

keywords

  • antitumor agents
  • inhibitors
  • kinetics
  • lactones
  • natural products
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Identity

International Standard Serial Number (ISSN)

  • 1439-4227

Digital Object Identifier (DOI)

  • 10.1002/cbic.201000205

PubMed ID

  • 20623569
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Additional Document Info

start page

  • 1692

end page

  • 1699

volume

  • 11

issue

  • 12

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