In vivo efficacy of natural product-inspired irreversible kinase inhibitors

Academic Article

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• Research
• Identity
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Overview

authors

• Barluenga, S.
• Jogireddy, R.
• Koripelly, G. K.
• Winssinger, Nicolas

publication date

• August 2010

journal

• ChemBioChem  Journal

subject areas

• Angiogenesis Inhibitors
• Animals
• Carcinoma, Renal Cell
• Cell Growth Processes
• Cell Line, Tumor
• Female
• Inhibitory Concentration 50
• Kidney Neoplasms
• Lactones
• Mice
• Mice, Inbred BALB C
• Protein Kinase Inhibitors
• Random Allocation
• Receptor, Platelet-Derived Growth Factor beta
• Vascular Endothelial Growth Factor Receptor-1
• Xenograft Model Antitumor Assays

Research

keywords

• antitumor agents
• inhibitors
• kinetics
• lactones
• natural products

Identity

International Standard Serial Number (ISSN)

• 1439-4227

Digital Object Identifier (DOI)

• 10.1002/cbic.201000205

PubMed ID

• 20623569

Additional Document Info

start page

• 1692

end page

• 1699

volume

• 11

issue

• 12