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Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase

Academic Article
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  • Overview
  • Identity
  • Additional Document Info
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Overview

authors

  • Scott, D. C.
  • Hammill, J. T.
  • Min, J.
  • Rhee, D. Y.
  • Connelly, M.
  • Sviderskiy, V. O.
  • Bhasin, D.
  • Chen, Y.
  • Ong, S. S.
  • Chai, S. C.
  • Goktug, A. N.
  • Huang, G.
  • Monda, J. K.
  • Low, J.
  • Kim, H. S.
  • Paulo, J. A.
  • Cannon, J. R.
  • Shelat, A. A.
  • Chen, T.
  • Kelsall, I. R.
  • Alpi, A. F.
  • Pagala, V.
  • Wang, X. S.
  • Peng, J.
  • Singh, B.
  • Harper, J. W.
  • Schulman, B. A.
  • Guy, Rodney Kiplin

publication date

  • August 2017

journal

  • Nature Chemical Biology  Journal

subject areas

  • Acetylation
  • Binding Sites
  • Dose-Response Relationship, Drug
  • Enzyme Inhibitors
  • Humans
  • Models, Molecular
  • Molecular Structure
  • NEDD8 Protein
  • Small Molecule Libraries
  • Structure-Activity Relationship
  • Ubiquitin-Protein Ligases
  • Ubiquitins
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Identity

PubMed Central ID

  • PMC5577376

International Standard Serial Number (ISSN)

  • 1552-4450

Digital Object Identifier (DOI)

  • 10.1038/nchembio.2386

PubMed ID

  • 28581483
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Additional Document Info

start page

  • 850

end page

  • 857

volume

  • 13

issue

  • 8

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