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Targeting protein tyrosine phosphatase SHP2 for the treatment of PTPN11-associated malignancies

Academic Article
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  • Identity
  • Additional Document Info
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Overview

authors

  • Yu, B.
  • Liu, W.
  • Yu, W. M.
  • Loh, M. L.
  • Alter, S.
  • Guvench, Olgun
  • MacKerell Jr., A. D.
  • Tang, L. D.
  • Qu, C. K.

publication date

  • September 2013

journal

  • Molecular Cancer Therapeutics  Journal

subject areas

  • Animals
  • Catalytic Domain
  • Cell Line
  • Cell Proliferation
  • Child
  • Drug Design
  • Drug Evaluation, Preclinical
  • Drug Screening Assays, Antitumor
  • Enzyme Inhibitors
  • Gene Knockout Techniques
  • Humans
  • Indoles
  • Leukemia, Myeloid
  • Mice
  • Molecular Structure
  • Mutation
  • Noonan Syndrome
  • Protein Tyrosine Phosphatase, Non-Receptor Type 11
  • Signal Transduction
  • Triazines
  • Tumor Cells, Cultured
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Identity

PubMed Central ID

  • PMC3769526

International Standard Serial Number (ISSN)

  • 1535-7163

Digital Object Identifier (DOI)

  • 10.1158/1535-7163.mct-13-0049-t

PubMed ID

  • 23825065
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Additional Document Info

start page

  • 1738

end page

  • 1748

volume

  • 12

issue

  • 9

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