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Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB

Academic Article
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  • Additional Document Info
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Overview

authors

  • Mallari, J. P.
  • Shelat, A. A.
  • Obrien, T.
  • Caffrey, C. R.
  • Kosinski, A.
  • Connelly, M.
  • Harbut, M.
  • Greenbaum, D.
  • McKerrow, J. H.
  • Guy, Rodney Kiplin

publication date

  • February 2008

journal

  • Journal of Medicinal Chemistry  Journal

subject areas

  • Animals
  • Cathepsin B
  • Cell Line
  • Cell Line, Tumor
  • Humans
  • Models, Molecular
  • Nitriles
  • Purines
  • Static Electricity
  • Structure-Activity Relationship
  • Trypanocidal Agents
  • Trypanosoma brucei brucei
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Identity

International Standard Serial Number (ISSN)

  • 0022-2623

Digital Object Identifier (DOI)

  • 10.1021/jm0707601

PubMed ID

  • 18173229
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Additional Document Info

start page

  • 545

end page

  • 552

volume

  • 51

issue

  • 3

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