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ToP-DNJ, a selective inhibitor of endoplasmic reticulum α-glucosidase II Exhibiting Antiflaviviral Activity

Academic Article
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Overview

authors

  • Kiappes Jr., John
  • Hill, M. L.
  • Alonzi, D. S.
  • Miller, J. L.
  • Iwaki, R.
  • Sayce, A. C.
  • Caputo, A. T.
  • Kato, A.
  • Zitzmann, N.

publication date

  • January 2018

journal

  • ACS Chemical Biology  Journal

subject areas

  • 1-Deoxynojirimycin
  • Administration, Oral
  • Animals
  • Antiviral Agents
  • Dengue Virus
  • Endoplasmic Reticulum
  • Glycoside Hydrolase Inhibitors
  • HL-60 Cells
  • Hepacivirus
  • Humans
  • Inhibitory Concentration 50
  • Liver
  • Male
  • Mice, Inbred BALB C
  • Rats
  • Tissue Distribution
  • Tocopherols
  • alpha-Glucosidases
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Identity

PubMed Central ID

  • PMC5824344

International Standard Serial Number (ISSN)

  • 1554-8929

Digital Object Identifier (DOI)

  • 10.1021/acschembio.7b00870

PubMed ID

  • 29161006
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Additional Document Info

start page

  • 60

end page

  • 65

volume

  • 13

issue

  • 1

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