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Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK

Academic Article
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  • Research
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Overview

authors

  • Dang, D. K.
  • Shin, E. J.
  • Nam, Y.
  • Ryoo, S.
  • Jeong, J. H.
  • Jang, Choon-Gon
  • Nabeshima, T.
  • Hong, J. S.
  • Kim, H. C.

publication date

  • January 2016

journal

  • Journal of Neuroinflammation  Journal
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Research

keywords

  • Cleaved PKC delta
  • Dopamine
  • Methamphetamine toxicity
  • Microglia of M1 phenotype
  • Mitochondria
  • Oxidative stress
  • Phosphorylation of ERK1/2
  • Pro-apoptosis
  • Striatum
  • p47phox knockout mice
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Identity

International Standard Serial Number (ISSN)

  • 1742-2094

Digital Object Identifier (DOI)

  • 10.1186/s12974-016-0478-x
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Additional Document Info

volume

  • 13

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