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Synthesis and evaluation of dibenzothiazepines: a novel class of selective cannabinoid-1 receptor inverse agonists

Academic Article
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  • Overview
  • Identity
  • Additional Document Info
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Overview

authors

  • Pettersson, H.
  • Bulow, A.
  • Ek, F.
  • Jensen, J.
  • Ottesen, L. K.
  • Fejzic, A.
  • Ma, J. N.
  • Del Tredici, Andria Lee
  • Currier, E. A.
  • Gardell, L. R.
  • Tabatabaei, A.
  • Craig, D.
  • McFarland, K.
  • Ott, T. R.
  • Piu, F.
  • Burstein, E. S.
  • Olsson, R.

publication date

  • April 2009

journal

  • Journal of Medicinal Chemistry  Journal

subject areas

  • Animals
  • Anti-Obesity Agents
  • Appetite Depressants
  • Cell Line
  • Combinatorial Chemistry Techniques
  • Dibenzothiazepines
  • Drug Inverse Agonism
  • Eating
  • Humans
  • Hypothermia
  • In Vitro Techniques
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Microsomes, Liver
  • Models, Molecular
  • Radioligand Assay
  • Rats
  • Rats, Sprague-Dawley
  • Receptor, Cannabinoid, CB1
  • Solubility
  • Structure-Activity Relationship
  • Thiazepines
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Identity

International Standard Serial Number (ISSN)

  • 0022-2623

Digital Object Identifier (DOI)

  • 10.1021/jm801534c

PubMed ID

  • 19338356
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Additional Document Info

start page

  • 1975

end page

  • 1982

volume

  • 52

issue

  • 7

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