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Mitochondrial biogenesis is impaired in osteoarthritis chondrocytes but reversible via peroxisome proliferator-activated receptor γ coactivator 1α.

Academic Article
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Overview

authors

  • Wang, Y.
  • Zhao, X.
  • Lotz, Martin
  • Terkeltaub, R.
  • Liu-Bryan, R.

publication date

  • August 2015

journal

  • Arthritis & Rheumatology  Journal

subject areas

  • AMP-Activated Protein Kinases
  • Animals
  • Cartilage, Articular
  • Chondrocytes
  • DNA-Binding Proteins
  • High Mobility Group Proteins
  • Humans
  • Knee Joint
  • Mice
  • Mitochondria
  • Mitochondrial Proteins
  • Nuclear Respiratory Factors
  • Osteoarthritis, Knee
  • Oxidative Phosphorylation
  • Phosphorylation
  • Signal Transduction
  • Sirtuin 1
  • Transcription Factors
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Identity

PubMed Central ID

  • PMC4519411

International Standard Serial Number (ISSN)

  • 2326-5191

Digital Object Identifier (DOI)

  • 10.1002/art.39182

PubMed ID

  • 25940958
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Additional Document Info

start page

  • 2141

end page

  • 2153

volume

  • 67

issue

  • 8

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