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Identification of TG100-115 as a new and potent TRPM7 kinase inhibitor, which suppresses breast cancer cell migration and invasion

Academic Article
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Overview

authors

  • Son, C.
  • Bae, Y.
  • Jun, J.
  • Lee, H.
  • Kim, N. D.
  • Lee, K. B.
  • Hur, Wooyoung
  • Park, J. Y.
  • Sim, T.

publication date

  • April 2017

journal

  • Biochimica Et Biophysica Acta-General Subjects  Journal

subject areas

  • Adenosine Triphosphate
  • Breast Neoplasms
  • Cell Line, Tumor
  • Cell Movement
  • Cell Proliferation
  • Cyclic AMP Response Element-Binding Protein
  • Female
  • Focal Adhesion Protein-Tyrosine Kinases
  • Humans
  • Neoplasm Invasiveness
  • Nonmuscle Myosin Type IIA
  • Phenols
  • Phosphorylation
  • Protein Kinase Inhibitors
  • Protein Serine-Threonine Kinases
  • Pteridines
  • TRPM Cation Channels
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Research

keywords

  • Breast cancer
  • Cell invasion
  • Cell migration
  • MDA-MB-231
  • TG100-115
  • TRPM7 kinase inhibitor
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Identity

International Standard Serial Number (ISSN)

  • 0304-4165

Digital Object Identifier (DOI)

  • 10.1016/jbbagen.2017.01.034

PubMed ID

  • 28161478
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Additional Document Info

start page

  • 947

end page

  • 957

volume

  • 1861

issue

  • 4

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