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Small-molecule ligands of GD2 ganglioside, designed from NMR studies, exhibit induced-fit binding and bioactivity

Academic Article
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Overview

authors

  • Tong, W.
  • Gagnon, M.
  • Sprules, T.
  • Gilbert, M.
  • Chowdhury, S.
  • Meerovitch, K.
  • Hansford, K.
  • Purisima, E. O.
  • Blankenship, John
  • Cheung, N. K. V.
  • Gehring, K.
  • Lubell, W. D.
  • Saragovi, H. U.

publication date

  • February 2010

journal

  • Chemistry & Biology  Journal

subject areas

  • Antibodies, Monoclonal
  • Binding Sites
  • Calcium
  • Computer Simulation
  • Enzyme-Linked Immunosorbent Assay
  • Epitope Mapping
  • Gangliosides
  • Ligands
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Peptides, Cyclic
  • src-Family Kinases
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Identity

International Standard Serial Number (ISSN)

  • 1074-5521

Digital Object Identifier (DOI)

  • 10.1016/j.chembiol.2010.01.012

PubMed ID

  • 20189108
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Additional Document Info

start page

  • 183

end page

  • 194

volume

  • 17

issue

  • 2

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