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Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis

Academic Article
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Overview

authors

  • Romero, R.
  • Sayin, V. I.
  • Davidson, S. M.
  • Bauer, M. R.
  • Singh, S. X.
  • LeBoeuf, Sarah
  • Karakousi, T. R.
  • Ellis, D. C.
  • Bhutkar, A.
  • Sanchez-Rivera, F. J.
  • Subbaraj, L.
  • Martinez, B.
  • Bronson, R. T.
  • Prigge, J. R.
  • Schmidt, E. E.
  • Thomas, C. J.
  • Goparaju, C.
  • Davies, A.
  • Dolgalev, I.
  • Heguy, A.
  • Allaj, V.
  • Poirier, J. T.
  • Moreira, A. L.
  • Rudin, C. M.
  • Pass, H. I.
  • Vander Heiden, M. G.
  • Jacks, T.
  • Papagiannakopoulos, T.

publication date

  • November 2017

journal

  • Nature Medicine  Journal

subject areas

  • Adenocarcinoma
  • Animals
  • Clustered Regularly Interspaced Short Palindromic Repeats
  • Genes, ras
  • Glutaminase
  • Glutamine
  • Humans
  • Hydrolysis
  • Kelch-Like ECH-Associated Protein 1
  • Lung Neoplasms
  • Mice
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Identity

PubMed Central ID

  • PMC5677540

International Standard Serial Number (ISSN)

  • 1078-8956

Digital Object Identifier (DOI)

  • 10.1038/nm.4407

PubMed ID

  • 28967920
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Additional Document Info

start page

  • 1362

end page

  • 1368

volume

  • 23

issue

  • 11

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