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Murine Monoclonal Antibodies against the Receptor Binding Domain of SARS-CoV-2 Neutralize Authentic Wild-Type SARS-CoV-2 as Well as B.1.1.7 and B.1.351 Viruses and Protect In Vivo in a Mouse Model in a Neutralization-Dependent Manner

Academic Article
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Overview

authors

  • Amanat, F.
  • Strohmeier, S.
  • Lee, W. H.
  • Bangaru, S.
  • Ward, Andrew
  • Coughlan, L.
  • Krammer, F.

publication date

  • July 27, 2021

journal

  • mBio  Journal

subject areas

  • Angiotensin-Converting Enzyme 2
  • Animals
  • Antibodies, Monoclonal
  • Antibodies, Neutralizing
  • Antibodies, Viral
  • COVID-19
  • Cercopithecus aethiops
  • Female
  • Humans
  • Mice
  • Mice, Inbred BALB C
  • Neutralization Tests
  • Protein Binding
  • Protein Domains
  • Receptors, Virus
  • SARS-CoV-2
  • Vero Cells
  • Viral Load
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Identity

PubMed Central ID

  • PMC8406178

International Standard Serial Number (ISSN)

  • 2150-7511

Digital Object Identifier (DOI)

  • 10.1128/mBio.01002-21

PubMed ID

  • 34311574
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Additional Document Info

volume

  • 12

issue

  • 4

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