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Modeling cystic fibrosis using pluripotent stem cell-derived human pancreatic ductal epithelial cells

Academic Article
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Overview

authors

  • Simsek, S.
  • Zhou, T.
  • Robinson, C. L.
  • Tsai, S. Y.
  • Crespo, M.
  • Amin, S.
  • Lin, X.
  • Hon, J.
  • Evans, T.
  • Chen, Shuibing

publication date

  • May 2016

journal

  • Stem Cells Translational Medicine  Journal

subject areas

  • Biosensing Techniques
  • Cell Differentiation
  • Cell Line
  • Cell Separation
  • Coculture Techniques
  • Cystic Fibrosis
  • Cystic Fibrosis Transmembrane Conductance Regulator
  • Epithelial Cells
  • Frameshift Mutation
  • Gene Expression Regulation
  • Genetic Markers
  • Genetic Predisposition to Disease
  • Humans
  • Induced Pluripotent Stem Cells
  • Pancreatic Ducts
  • Phenotype
  • RNA Splicing
  • Time Factors
  • Transfection
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Research

keywords

  • Chloride ion efflux assay
  • Directed differentiation
  • Pancreatic defects of cystic fibrosis
  • Reprogramming
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Identity

PubMed Central ID

  • PMC4835252

International Standard Serial Number (ISSN)

  • 2157-6564

Digital Object Identifier (DOI)

  • 10.5966/sctm.2015-0276

PubMed ID

  • 27034411
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Additional Document Info

start page

  • 572

end page

  • 579

volume

  • 5

issue

  • 5

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