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Discovery of a noncovalent, mutant-selective epidermal growth factor receptor inhibitor

Academic Article
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  • Identity
  • Additional Document Info
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Overview

authors

  • Chan, B. K.
  • Hanan, E. J.
  • Bowman, K. K.
  • Bryan, Marian C
  • Burdick, D.
  • Chan, E.
  • Chen, Y.
  • Clausen, S.
  • Dela Vega, T.
  • Dotson, J.
  • Eigenbrot, C.
  • Elliott, R. L.
  • Heald, R. A.
  • Jackson, P. S.
  • Knight, J. D.
  • La, H.
  • Lainchbury, M. D.
  • Malek, S.
  • Purkey, Hans
  • Schaefer, G.
  • Schmidt, S.
  • Seward, E. M.
  • Sideris, S.
  • Shao, L.
  • Wang, S.
  • Yeap, S. K.
  • Yen, I.
  • Yu, C.
  • Heffron, T. P.

publication date

  • October 2016

journal

  • Journal of Medicinal Chemistry  Journal

subject areas

  • Animals
  • Antineoplastic Agents
  • Carcinoma, Non-Small-Cell Lung
  • Cell Line, Tumor
  • Cell Proliferation
  • Crystallography, X-Ray
  • Drug Resistance, Neoplasm
  • Humans
  • Lung
  • Lung Neoplasms
  • Mice
  • Models, Molecular
  • Mutation
  • Protein Kinase Inhibitors
  • Receptor, Epidermal Growth Factor
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Identity

International Standard Serial Number (ISSN)

  • 0022-2623

Digital Object Identifier (DOI)

  • 10.1021/acs.jmedchem.6b00995

PubMed ID

  • 27564586
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Additional Document Info

start page

  • 9080

end page

  • 9093

volume

  • 59

issue

  • 19

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