Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form

Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1

Academic Article
uri icon
  • Overview
  • Identity
  • Additional Document Info
  • View All
scroll to property group menus

Overview

authors

  • Zheng, Z.
  • Guo, Y.
  • Novak, O.
  • Dai, X.
  • Zhao, Y.
  • Ljung, K.
  • Noel, J. P.

publication date

  • 2013

journal

  • Nature Chemical Biology  Journal

abstract

  • We identify an Arabidopsis pyridoxal-phosphate-dependent aminotransferase, VAS1, whose loss-of-function simultaneously increases amounts of the phytohormone auxin and the ethylene precursor 1-aminocyclopropane-1-carboxylate. VAS1 uses the ethylene biosynthetic intermediate methionine as an amino donor and the auxin biosynthetic intermediate indole-3-pyruvic acid as an amino acceptor to produce L-tryptophan and 2-oxo-4-methylthiobutyric acid. Our data indicate that VAS1 serves key roles in coordinating the amounts of these two vital hormones.

subject areas

  • Amino Acid Sequence
  • Amino Acids, Cyclic
  • Arabidopsis
  • Arabidopsis Proteins
  • Ethylenes
  • Indoleacetic Acids
  • Indoles
  • Methionine
  • Molecular Sequence Data
  • Mutation
  • Pyridoxal Phosphate
  • Transaminases
  • Tryptophan
scroll to property group menus

Identity

PubMed Central ID

  • PMC3948326

International Standard Serial Number (ISSN)

  • 1552-4450

Digital Object Identifier (DOI)

  • 10.1038/nchembio.1178

PubMed ID

  • 23377040
scroll to property group menus

Additional Document Info

start page

  • 244

end page

  • 246

volume

  • 9

issue

  • 4

©2019 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support