Disrupting acetyl-lysine recognition: progress in the development of bromodomain inhibitors
Academic Article
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Overview
publication date
- 2016
journal
- Journal of Medicinal Chemistry Journal
subject areas
- ATPases Associated with Diverse Cellular Activities
- Acetylation
- Adaptor Proteins, Signal Transducing
- Adenosine Triphosphatases
- Animals
- Antigens, Nuclear
- CREB-Binding Protein
- Carrier Proteins
- Chromosomal Proteins, Non-Histone
- DNA Helicases
- DNA-Binding Proteins
- Drug Discovery
- Histones
- Humans
- Lysine
- Models, Molecular
- Nerve Tissue Proteins
- Nuclear Proteins
- Protein Processing, Post-Translational
- Protein-Serine-Threonine Kinases
- RNA-Binding Proteins
- Small Molecule Libraries
- Transcription Factors