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Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain

Academic Article
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  • Identity
  • Additional Document Info
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Overview

authors

  • Stachel, S. J.
  • Sanders, J. M.
  • Henze, D. A.
  • Rudd, M. T.
  • Su, H. P.
  • Li, Yiwei
  • Nanda, K. K.
  • Egbertson, M. S.
  • Manley, P. J.
  • Jones, K. L. G.
  • Brnardic, E. J.
  • Green, A.
  • Grobler, J. A.
  • Hanney, B.
  • Leitl, M.
  • Lai, M. T.
  • Munshi, V.
  • Murphy, D.
  • Rickert, K.
  • Riley, D.
  • Krasowska-Zoladek, A.
  • Daley, C.
  • Zuck, P.
  • Kane, S. A.
  • Bilodeau, M. T.

publication date

  • July 2014

journal

  • Journal of Medicinal Chemistry  Journal

subject areas

  • Animals
  • Chronic Pain
  • Drug Evaluation, Preclinical
  • Humans
  • Indoles
  • Ligands
  • Models, Molecular
  • Protein Kinase Inhibitors
  • Pyrimidines
  • Rats
  • Receptor, trkA
  • Small Molecule Libraries
  • Structure-Activity Relationship
  • Triazoles
  • Urea
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Identity

International Standard Serial Number (ISSN)

  • 0022-2623

Digital Object Identifier (DOI)

  • 10.1021/jm5006429

PubMed ID

  • 24914455
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Additional Document Info

start page

  • 5800

end page

  • 5816

volume

  • 57

issue

  • 13

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