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X-ray structures of the LXRα LBD in its homodimeric form and implications for heterodimer signaling

Academic Article
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  • Research
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Overview

authors

  • Fradera, X.
  • Vu, D.
  • Nimz, O.
  • Skene, R.
  • Hosfield, David J
  • Wynands, R.
  • Cooke, A. J.
  • Haunso, A.
  • King, A.
  • Bennett, D. J.
  • McGuire, R.
  • Uitdehaag, J. C. M.

publication date

  • May 2010

journal

  • Journal of Molecular Biology  Journal

subject areas

  • Benzoates
  • Benzylamines
  • Binding Sites
  • Crystallography, X-Ray
  • Dimerization
  • Isoxazoles
  • Ligands
  • Liver X Receptors
  • Models, Molecular
  • Orphan Nuclear Receptors
  • Phenylacetates
  • Sequence Alignment
  • Signal Transduction
  • Thiazoles
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Research

keywords

  • GW3965
  • cholesterol
  • crystal
  • helix 12
  • interface
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Identity

International Standard Serial Number (ISSN)

  • 0022-2836

Digital Object Identifier (DOI)

  • 10.1016/j.jmb.2010.04.005

PubMed ID

  • 20382159
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Additional Document Info

start page

  • 120

end page

  • 132

volume

  • 399

issue

  • 1

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