The evolution of cefotaximase activity in the TEM β-lactamase

Academic Article

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• Research
• Identity
• Additional Document Info
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Overview

authors

• Singh, M. K.
• Dominy, Brian

publication date

• January 2012

journal

• Journal of Molecular Biology  Journal

subject areas

• Anti-Bacterial Agents
• Binding Sites
• Catalysis
• Crystallography, X-Ray
• Drug Resistance, Bacterial
• Evolution, Molecular
• Hydrogen Bonding
• Kinetics
• Models, Molecular
• Molecular Dynamics Simulation
• Point Mutation
• Protein Binding
• Protein Conformation
• beta-Lactamases

Research

keywords

• MM-GBSA
• TEM beta-lactamase
• catalytic activity
• enzymatic evolution
• molecular dynamics

Identity

International Standard Serial Number (ISSN)

• 0022-2836

Digital Object Identifier (DOI)

• 10.1016/j.jmb.2011.10.041

PubMed ID

• 22075446

Additional Document Info

start page

• 205

end page

• 220

volume

• 415

issue

• 1