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Structure-based redesign of GST A2-2 for enhanced catalytic efficiency with azathioprine

Academic Article
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Overview

authors

  • Zhang, W.
  • Moden, O.
  • Tars, K.
  • Mannervik, Bengt

publication date

  • March 2012

journal

  • Chemistry & Biology  Journal

subject areas

  • Azathioprine
  • Binding Sites
  • Biocatalysis
  • Catalytic Domain
  • Computer Simulation
  • Crystallography, X-Ray
  • Glutathione Transferase
  • Humans
  • Hydrogen-Ion Concentration
  • Kinetics
  • Point Mutation
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Identity

International Standard Serial Number (ISSN)

  • 1074-5521

Digital Object Identifier (DOI)

  • 10.1016/j.chembiol.2012.01.021

PubMed ID

  • 22444596
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Additional Document Info

start page

  • 414

end page

  • 421

volume

  • 19

issue

  • 3

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