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An improved zinc-finger nuclease architecture for highly specific genome editing

Academic Article
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Overview

authors

  • Miller, J. C.
  • Holmes, M. C.
  • Wang, J.
  • Guschin, D. Y.
  • Lee, Y. L.
  • Rupniewski, Igor
  • Beausejour, C. M.
  • Waite, A. J.
  • Wang, Nathaniel
  • Kim, K. A.
  • Gregory, P. D.
  • Pabo, C. O.
  • Rebar, E. J.

publication date

  • July 2007

journal

  • Nature Biotechnology  Journal

subject areas

  • Base Sequence
  • Binding Sites
  • Biotechnology
  • Catalysis
  • Deoxyribonucleases, Type II Site-Specific
  • Dimerization
  • Genome
  • Green Fluorescent Proteins
  • Humans
  • K562 Cells
  • Models, Biological
  • Molecular Conformation
  • Molecular Sequence Data
  • Protein Structure, Tertiary
  • Zinc Fingers
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Identity

International Standard Serial Number (ISSN)

  • 1087-0156

Digital Object Identifier (DOI)

  • 10.1038/nbt1319

PubMed ID

  • 17603475
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Additional Document Info

start page

  • 778

end page

  • 785

volume

  • 25

issue

  • 7

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